Anti-ECSIT antibody （ab21288）抗ECSIT抗體產(chǎn)品信息：

• Product nameAnti-ECSIT antibody
• Description

  Rabbit polyclonal to ECSIT

• Tested applicationsICC/IF, IP, IHC-P, WB
• Species reactivity

  Reacts with: Mouse, Human

• Immunogen

  Synthetic peptide corresponding to 14 amino acids near the C-terminus of ECSIT (Human).

• Positive control
  • human heart lysate

Properties

• FormLiquid
• Storage instructionsStore at +4°C.
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: PBS

• Concentration 100 µg at 1 mg/ml

• Purification notesIon exchange chromatography.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Signal Transduction
  • Signaling Pathway
  • Nuclear Signaling
  • NFkB Pathway
  • Immunology
  • Innate Immunity
  • TLR Signaling

Applications

Our Abpromise guarantee covers the use of ab21288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

• FunctionAdapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.
• Sequence similaritiesBelongs to the ECSIT family.
• Cellular localizationCytoplasm. Nucleus. Mitochondrion.

• Database links

  • Entrez Gene: 51295 Human
  • Entrez Gene: 26940 Mouse
  • Omim: 608388 Human
  • SwissProt: Q9BQ95 Human
  • SwissProt: Q9QZH6 Mouse
  • Unigene: 515146 Human
  • Unigene: 425568 Mouse

• Alternative names

  • Ecsit antibody
  • ECSIT homolog antibody
  • ECSIT protein antibody

Anti-ECSIT antibody images

• 

  Western blot - ECSIT antibody (ab21288)

  Lane 1 : Anti-ECSIT antibody (ab21288) at 0.5 µg/ml
  Lane 2 : Anti-ECSIT antibody (ab21288) at 1 µg/ml
  Lane 3 : Anti-ECSIT antibody (ab21288) at 2 µg/ml
  
  Lane 1 : human heart lysate
  Lane 2 : human heart lysate
  Lane 3 : human heart lysate
  
  
  Predicted band size : 49 kDa
  Observed band size : 42 kDa (why is the actual band size different from the predicted?)

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ECSIT antibody (ab21288)

  ab21288 at 2µg/ml staining ECSIT in mouse heart by IHC

公司介紹：

    Abcam位于英國的劍橋科學園，成立于1998年，專門生產(chǎn)和分銷研究型抗體。主要創(chuàng)立人Jonathan Milner和實驗室同事構思成立一間了解科研人員需要的網(wǎng)上抗體公司，理念是Abcam銷售質量高的抗體，并提供zui全面、誠實、時新的說明書，快速的送貨服務，及高效率的顧客和服務。我們的在線目錄(m.0558dmc.com) 已有差不多100,000種抗體和試劑，并不斷添加，供應予百多個國家。Abcam于2005年11月在倫敦證券交易所上市，在美國馬薩諸塞州、日本東京及香港均設有分公司。

    Abcam 一直致力加強產(chǎn)品線，為使研究員更容易找到蛋白質研究試劑產(chǎn)品，在2011并購了美國的MitoSciences公司，加強了免疫分析方面的產(chǎn)品供應；同年也并購了英國的Ascent Scientific 公司，開展了生化試劑的供應。在2012年，Abcam并購了美國的Epitomics 公司，成為一家有的RabMAbs® 供應商。

    Abcam 的 目標是給世界上的抗體建立zui大的在線目錄，為各地科學家提供*產(chǎn)品，成為各國科學界的重要伙伴。我們?yōu)樗挟a(chǎn)品提供來使客戶獲得預期的結 果。為提供高質量的抗體來指向盡可能多的靶蛋白，我們盡所能在盡可能多的應用和物種中檢測每種抗體。我們相信誠信才是上策，在我們的上會發(fā)布有關我們 每一種產(chǎn)品的盡可能多的信息。

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